Director / Principal Investigator, AI and Genomics

With the world's largest database of more than eleven million genotyped participants, the 23andMe Research Institute is at the forefront of using human genetics to advance biomedical research and transform healthcare. We are seeking a Director-level Principal Investigator to establish and lead our AI innovation efforts, building population-scale foundation models on a data substrate that exists nowhere else. Who We Are We are a group of individuals passionate about genetic discovery. 23andMe Research Institute is a nonprofit medical research organization that enables people everywhere to access their genetic information, learn about themselves, and participate in the world's largest crowdsourced research initiative. The Institute aims to be the world's most significant contributor to scientific advancement, uniting people with the common goal of improving health and deepening our understanding of DNA — the code of life. What You'll Do You will set and own the scientific vision for AI at the 23andMe Research Institute, and be accountable for translating it into research output and external funding. You will build and lead a research group of your own, beginning with two founding scientists recruited under your direction, and grow it in step with the funding you secure. Your research agenda will span three complementary areas: health-risk prediction, developing foundation models that forecast individual health outcomes from genetic and longitudinal data, building on our existing PRSformer and Next Health Event work; variant-effect prediction, interpreting the functional and clinical consequences of genetic variants including variants of uncertain significance, in preparation for a product line based on whole-genome sequencing. You will represent the Institute's AI work externally and raise grant, philanthropic, and industry funding to support the group's expansion. …

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